Add 2 ½ cups of blueberries, sugar, and orange juice to a medium sauce pan.
Cut the vanilla bean down the middle and use a spoon to scrape out the seeds and add them to the saucepan. Throw the empty vanilla bean pod in for extra flavor.
Stir to combine and bring to a boil. Reduce to a low simmer and let cook for 15-20 minutes until thickened. Stir occasionally.
Using the back of your spoon, lightly mash some of the blueberries. It helps to release the juices. A few minutes before it's done, add the remaining ½ cup of blueberries for texture.
Take the compote off the heat and remove the vanilla bean pod from the sauce.